Daoqiang Zhang, Professor, Nanjing University of Aeronautics and Astronautics
张道强,教授,南京航空航天大学
“优秀青年科学基金”获得者
Title:Neuroimaging-Genetics Association Analysis Based on Sparse Learning
Abstract:
Imaging Genetics studies how genes influence psychopathology and use functional neuroimaging to investigate genes that are
expressed in the brain. Recent technological advance in machine learning community has enabled new approaches to study genetic
effects on brain for improving understanding of disease mechanism, early diagnosis and treatment response for brain disorders.
In this talk, using Alzheimer's disease (AD) as an example, I will first briefly introduce some background of imaging genetics and
exciting traditional statistical methods in clinical research. And then I will describe our multivariate genetic association analysis
strategies to boost the detection power when taking into account the inherent structure among genotypes or phenotypes as priori
knowledge. I will also present our recent study on the development of a framework for identifying multi-modal imaging phenotypes
serving as intermediate traits when given disease status and its corresponding related risk gene. Finally current challenges and
Future research directions will be highlighted and discussed in the end of the talk.
Brief Bio:
Daoqiang Zhang received the B.Sc. and Ph.D. degrees in Computer Science from Nanjing University of Aeronautics and
Astronautics, China, in 1999 and 2004, respectively. He joined the Department of Computer Science and Engineering of Nanjing
University of Aeronautics and Astronautics in 2004, and is a professor at present. His research interests include machine learning,
pattern recognition, data mining, and medical image analysis. In these areas he has published over 100 technical papers in referred
journals or conference proceedings, including reputable international journals such as Neuroimage, Human Brain Mapping (HBM),
etc., and top-tier international conferences such as MICCAI, IJCAI, AAAI, etc., with 4500+ citations by Google Scholar. He was
nominated for the National Excellent Doctoral Dissertation Award of China in 2006, and won the best paper award at the 9th
Pacific Rim International Conference on Artificial Intelligence (PRICAI'06). He served as a program committee member for
several international and native conferences. He is a member of Chinese Association of Artificial Intelligence (CAAI) Machine
Learning Society.